Differential dehydration effects on globular proteins and intrinsically disordered proteins during film formation

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Differential dehydration effects on globular proteins and intrinsically disordered proteins during film formation

Globular proteins composed of different secondary structures and fold types were examined by synchrotron radiation circular dichroism spectroscopy to determine the effects of dehydration on their secondary structures. They exhibited only minor changes upon removal of bulk water during film formation, contrary to previously reported studies of proteins dehydrated by lyophilization (where substan...

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ژورنال

عنوان ژورنال: Protein Science

سال: 2017

ISSN: 0961-8368

DOI: 10.1002/pro.3118